Research & Sources – The scientific foundation of PetElixir™

Why we disclose our sources

The pet supplement market is full of big words and thin evidence. We take the opposite path.

Every PetElixir™ formula is created on the basis of published, peer-reviewed research – from human medicine, where liposomal technology has been studied for decades, and from veterinary science, which shows which nutrient groups genuinely support dogs and cats. The following selection shows key works we drew on during development. To protect our know-how, we name groups of active ingredients, not our specific formulas.

Human research on liposomal technology

The encapsulation of active substances in phospholipid shells was discovered and described in human research and refined over decades – all the way to the lipid nanoparticles of modern vaccine technology. Read here how NanoLipoX™ builds precisely on this.

1. Bangham, A. D.; Standish, M. M.; Watkins, J. C. (1965): Diffusion of univalent ions across the lamellae of swollen phospholipids. Journal of Molecular Biology, 13(1), 238–252. DOI: 10.1016/S0022-2836(65)80093-6 – The first description of liposomes.
2. Allen, T. M.; Cullis, P. R. (2013): Liposomal drug delivery systems: from concept to clinical applications. Advanced Drug Delivery Reviews, 65(1), 36–48. DOI: 10.1016/j.addr.2012.09.037
3. Akbarzadeh, A. et al. (2013): Liposome: classification, preparation, and applications. Nanoscale Research Letters, 8, 102. DOI: 10.1186/1556-276X-8-102
4. Bozzuto, G.; Molinari, A. (2015): Liposomes as nanomedical devices. International Journal of Nanomedicine, 10, 975–999. DOI: 10.2147/IJN.S68861
5. Sercombe, L. et al. (2015): Advances and challenges of liposome assisted drug delivery. Frontiers in Pharmacology, 6, 286. DOI: 10.3389/fphar.2015.00286
6. Hou, X.; Zaks, T.; Langer, R.; Dong, Y. (2021): Lipid nanoparticles for mRNA delivery. Nature Reviews Materials, 6(12), 1078–1094. DOI: 10.1038/s41578-021-00358-0

Veterinary sources

These works document how widespread joint, kidney and digestive topics are in dogs and cats – and which nutrient groups have been examined in studies.

1. Johnston, S. A. (1997): Osteoarthritis: joint anatomy, physiology, and pathobiology. Veterinary Clinics of North America: Small Animal Practice, 27(4), 699–723. DOI: 10.1016/S0195-5616(97)50076-3
2. Roush, J. K. et al. (2010): Multicenter veterinary practice assessment of the effects of omega-3 fatty acids on osteoarthritis in dogs. Journal of the American Veterinary Medical Association, 236(11), 1191–1197. DOI: 10.2460/javma.236.11.1191
3. O’Neill, D. G. et al. (2014): Prevalence of disorders recorded in dogs attending primary-care veterinary practices in England. PLoS ONE, 9(3), e90501. DOI: 10.1371/journal.pone.0090501
4. Marino, C. L. et al. (2014): Prevalence and classification of chronic kidney disease in cats randomly selected from four age groups. Journal of Feline Medicine and Surgery, 16(6), 465–472. DOI: 10.1177/1098612X13511446
5. Suchodolski, J. S. (2011): Microbes and gastrointestinal health of dogs and cats. Journal of Animal Science, 89(5), 1520–1530. DOI: 10.2527/jas.2010-3377

This list is a selection and is continuously expanded. The studies named describe basic research and veterinary findings – they are not statements about individual PetElixir™ products. Our products are complementary feed, not medicines; if your animal shows signs of illness, it belongs in veterinary care.

From knowledge to product

Reading research is one thing. Translating it into a product that an animal gladly takes and a body truly uses is another. Precisely this step – encapsulating selected nutrients in nanoliposomes, produced in small, controlled batches with pharmaceutical care in Vienna – is our craft. Find out here which groups of active ingredients benefit most.